性別：男

最高學(xué)歷：博士

系室：化學(xué)系

招生專業(yè)：化學(xué)、材料與化工、藥學(xué)

QQ：1594093981

郵箱：008940@csust.edu.cn

教育背景及學(xué)習(xí)經(jīng)歷：

2021.07 – 2023.09      中國(guó)科學(xué)院杭州醫(yī)學(xué)研究所             基礎(chǔ)醫(yī)學(xué)/博士后

2016.09 – 2021.05      湖南大學(xué)化學(xué)化工學(xué)院                   分析化學(xué)/博士

2014.09 – 2016.06      湖南大學(xué)化學(xué)化工學(xué)院                   分析化學(xué)/碩士

2010.09 – 2014.06      湖南中醫(yī)藥大學(xué)藥學(xué)院                    藥學(xué)/學(xué)士

科研情況：

? 主要研究方向：

1、生物醫(yī)藥與化學(xué)生物傳感

2、納米藥物載體的構(gòu)建與應(yīng)用

3、靶向核藥與抗體偶聯(lián)藥物腫瘤治療

? 近5年科研項(xiàng)目：

1、國(guó)家自然科學(xué)基金青年項(xiàng)目，二級(jí)結(jié)構(gòu)編碼三鏈功能核酸耦合納米孔技術(shù)及其在阿爾茲海默癥早期篩查中的應(yīng)用，執(zhí)行時(shí)間：2022.01-2024.12；主持。

? 近5年科研論文：

1.Le Yang, Hongye Wei, Zhihe Qing, Linlin Wu. AuNP@DNA nanoflares: Preparation and application in bioanalysis and biomedicine, Chinese Chemical Letters. 2024, https://doi.org/10.1016/j.cclet.2024.110524. (SCI一區(qū))

2. Le Yang, Zhihe Qing* Changhui Liu, Qiao Tang, Jishan Li, Sheng Yang, Jing Zheng, Ronghua Yang* and Weihong Tan. Direct fluorescent detection of blood potassium by ion-selective formation of intermolecular G-quadruplex and ligand binding. Analytical Chemistry, 2016, 88, 9285-9292. (SCI一區(qū))

3. Le Yang?, Jing Zheng?, Zhen Zou, Haiyan Cai, Peng Qi, Zhihe Qing, Qi Yan, Liping Qiu, Weihong Tan and Ronghua Yang*. Human serum albumin as an intrinsic signal amplification amplifier for ultrasensitive assays of the prostate-specific antigen in human plasma. Chemical Communications, 2020, 56, 1834-1846. (SCI二區(qū))

4. Liu, Jin?; Yang, Le?; Xue, Caoye?; Huang, Ge; Chen, Shiya; Zheng, Jing*; Yang, Ronghua ; Reductase and Light Programmatical Gated DNA Nanodevice for Spatiotemporally Controlled Imaging of Biomolecules in Subcellular Organelles under Hypoxic Conditions, ACS Applied Materials & Interfaces, 2021, 13(29): 33894-33904. (SCI一區(qū))

5. Zhen Zou?, Xiaodou Liao?, Le Yang?, Ziyun Huang, Hua Yang, Qi Yan, Yufei Zhang, Zhihe Qing, Lihua Zhang, Feng Feng, and Ronghua Yang*. Human serum albumin-occupying-based fluorescence turn-on analysis of antiepileptic drug tiagabine hydrochloride. Analytical Chemistry, 2020, 92, 3535-3562. (SCI一區(qū))

6. Qing Wei, Teng Yang, Jiayu Zhu, Ziwen Zhang, Le Yang, Yuchao Zhang, Can Hu, Jiahui Chen, Jinchao Wang, Xuefei Tian, Takaya Shimura, Jianmin Fang, Jieer Ying, Mengyang Fan, Peng Guo, Xiangdong Cheng. Spatiotemporal quantification of HER2-targeting antibody-drug conjugate bystander activity and enhancement of solid tumor penetration, Clinical Cancer Research. 2024, 30 (5): 984-997. (SCI一區(qū))

教學(xué)情況:

主講本科生《分析化學(xué)》、《分析化學(xué)實(shí)驗(yàn)》。