科研情況： ? 主要研究方向： 1、生物醫(yī)藥與化學(xué)生物傳感 2、POCT(即時(shí)檢測)產(chǎn)品的設(shè)計(jì)與實(shí)際應(yīng)用 3、納米藥物載體的構(gòu)建與應(yīng)用 ? 近5年科研項(xiàng)目： 1、國家自然科學(xué)基金青年項(xiàng)目，核酸適體介導(dǎo)的鄰近共價(jià)標(biāo)記體系用于細(xì)胞生理活動(dòng)的精準(zhǔn)監(jiān)測，執(zhí)行時(shí)間：2024.01-2026.12；主持。 ? 近5年科研論文： 1.Kun Chen; Jiamin Cai; Sujuan Wang; et al. Aptamer inhibits tumor growth by leveraging cellular proteasomal degradation system to degrade c‐Met in mice, Angewandte Chemie International Edition, 2022, 62(2): e202208451. 2. Kun Chen; Qin Huang; Ting Fu; et al. MicroRNA-initiated and intracellular Na+-fueled DNAzyme motor for differentiating molecular subtypes of nonsmall cell lung cancer, Analytical Chemistry, 2020, 92(11): 7404-7408. 3. Kun Chen; Ting Fu; Weidi Sun; et al. DNA-supramolecule conjugates in theranostics, Theranostics, 2019, 9(11): 3262-3279 4. Kun Chen; Shuai Xu; Zhiling Song; et al. Trimethyl Lock Quinone-Based Organic Molecular Probes for NQO1 Sensing and Imaging. Chemosensors, 2023, 11(4): 221. 5. Chan Yang; Kun Chen; Mei Chen; et al. Nanoscale metal-organic framework based two-photon sensing platform for bioimaging in live tissue, Analytical Chemistry, 2019, 91(4): 2727-2733. |
