姓 名：卿志和

職 稱：教授

導(dǎo)師資格：博士生導(dǎo)師

郵 箱：qingzhihe@hnu.edu.cn

電 話：0731-85258649

研究方向：生物傳感與健康分析

簡介：卿志和，教授，博士生導(dǎo)師，國家優(yōu)秀青年科學(xué)基金獲得者，“細(xì)胞化學(xué)”湖南省重點(diǎn)實(shí)驗(yàn)室常務(wù)副主任，“健康化學(xué)”湖南省普通高等學(xué)校科技創(chuàng)新團(tuán)隊(duì)帶頭人，長沙理工大學(xué)“湖湘學(xué)者”拔尖人才、科技處副處長、化學(xué)化工學(xué)院教授委員會(huì)主任、化學(xué)生物學(xué)專業(yè)負(fù)責(zé)人，入選全球前2%頂尖科學(xué)家榜單。從事生物傳感與健康分析研究工作，已主持國家自然科學(xué)基金優(yōu)青項(xiàng)目、面上項(xiàng)目，湖南省自然科學(xué)基金重點(diǎn)項(xiàng)目、優(yōu)青項(xiàng)目、企業(yè)技術(shù)服務(wù)項(xiàng)目等課題10余項(xiàng)，在 PNAS、Angew Chem、Anal Chem、等國內(nèi)外高水平期刊上發(fā)表SCI收錄論文80余篇，授權(quán)專利10余件。獲得湖南省自然科學(xué)一等獎(jiǎng)、湖南省自然科學(xué)二等獎(jiǎng)、湖南省青年科技獎(jiǎng)、湖南省教育系統(tǒng)優(yōu)秀共產(chǎn)黨員、湖南省優(yōu)秀研究生導(dǎo)師等獎(jiǎng)勵(lì)或榮譽(yù)。擔(dān)任Chinese Chemical Letters、The Innovation、Journal of Analysis and Testing、《分析試驗(yàn)室》等國內(nèi)外期刊的編委或青年編委。

代表性論文：

[1] Quan Ke; Li Xiaoyuan; Deng Jiaqi; Chen Weiju; Zou Zhen; Chen Kun; Wu Linlin; Liu Juewen;Qing Zhihe*. Pt-Decorated Gold Nanoflares for High-Fidelity Phototheranostics: Reducing Side-Effects and Enhancing Cytotoxicity toward Target Cells, Angew. Chem. Int. Ed. 2024, 63, e202402881.

[2] Yanli Lei, Chuangchuang Li, Xinyue Ji, Haiyan Sun, Xiaowen Liu, Zenghui Mao, Weiju Chen, Zhihe Qing,* and Juewen Liu. Lowering Entropic Barriers in Triplex DNA Switches Facilitating Biomedical Applications at Physiological pH. Angew. Chem. Int. Ed. 2024, 63 , e202402123.

[3] Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang,* Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing,* Ronghua Yang*. A Polymeric Nanobeacon for Revealing Hydrogen Polysulfides Fluctuation during Fertilization and Embryonic Development. Angew. Chem. Int. Ed. 2022, 61, e202114504.

[4] Zhen Zou, Libei He, Xiangxi Deng, Huangxiang Wang, Ziyun Huang, Qian Xue, Zhihe Qing*, Yanli Lei, Ronghua Yang*, and Juewen Liu. Zn2+-Coordination-Driven RNAAssembly with Retained Integrity and Biological Functions. Angew. Chem. Int. Ed. 2021, 60, 22970–22976.

[5] Lifang Chen, Shuohui Xing, Yanli Lei, Qiaoshu Chen, Zhen Zou, Ke Quan, Zhihe Qing*, Juewen Liu, and Ronghua Yang*. A Glucose-Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections. Angew. Chem. Int. Ed. 2021, 60, 23534–23539.

[6] Zhihe Qing, Guoyan Luo, Shuohui Xing, Zhen Zou, Yanli Lei, Juewen Liu*, Ronghua Yang*. Pt-S Bond Mediated Nanoflares for High-Fidelity Intracellular Applications by Avoiding Thiol Cleavage. Angew. Chem. Int. Ed.2020, 59, 14044 –14048.

[7] Zhihe Qing*, Jinlei Hu, Jingyuan Xu, Zhen Zou, Yanli Lei, Taiping Qing, Ronghua Yang*. An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability. Chem. Sci. 2020, 11, 1985–1990.

[8] Zhihe Qing*, Jingyuan Xu, Jing Zheng, Lei He, Zhen Zou, Sheng Yang, Weihong Tan, Ronghua Yang*. In Situ Amplification-Based Imaging of RNA in Living Cells. Angew. Chem. Int. Ed. 2019, 58, 11574–11585.