
姓 名:全珂
職 稱:副教授
導師資格:碩士生導師
郵 箱:quanke518@126.com
電 話:15675185142
研究方向:(1) 基于CRISPR-Cas系統(tǒng)的便攜式檢測新方法的構(gòu)建;(2)功能核酸/納米酶在食品安全分析中的應(yīng)用;(3)治病菌的可視化檢測與防控
簡介:全珂,理學博士,碩士生導師。長沙理工大學“湖湘學者”青年英才,獲評長沙理工大學優(yōu)秀黨支部書記、“雙帶頭人”標兵。主持國家自然科學基金青年項目、湖南省自然科學基金青年項目、長沙市自然科學基金(優(yōu)先資助)、湖南省教育廳優(yōu)青項目等課題共6項。在JACS、Angew. Chem. Int. Ed.、 Chem. Sci.、CCS Chem.等SCI期刊發(fā)表論文40余篇。指導學生獲得全國大學生生命科學競賽全國三等獎2項,省級三等獎2項。
代表性論文:
(1) Quan Ke; Li Xiaoyuan; Deng Jiaqi; Chen Weiju; Zou Zhen; Chen Kun; Wu Linlin; Liu Juewen;Qing Zhihe*. Pt-Decorated Gold Nanoflares for High-Fidelity Phototheranostics: Reducing Side-Effects and Enhancing Cytotoxicity toward Target Cells, Angewandte Chemie International Edition, 2024, 63:e202402881.
(2) Gao Yuan; Bai Bingfeng; Mao Zenghui; Yang Xiao; Shi Yi; Zhang Bo; Quan Ke*; Qing Zhihe*. An all-in-one Smartphone-assisted Ratiometric Fluorescent Device for Visual and Quantitative Detection of Glutathione, Talanta, https://doi.org/10.1016/j.talanta.2024.126805
(3) Quan Ke; Zeng Yuqing; Zhang Wenke; Li Fengfeng; Li Mengjiao; Qing Zhihe*. One-step, reagent-free construction of nano-enzyme as visual and reusable biosensor for oxidase substrates, Analytica Chimica Acta, 2024, 1285: 342008.
(4) Quan Ke; Tong Jiajie; Chen Lifang; Fang Shuyao; Li Mengjiao; Wu Linlin; Qing Zhihe*. Freezing-directed construction of enzyme/nano interfaces: Reagentless conjugation, superior activity, and better stability, Chinese Chemical Letters, 2024, 35: 108894.
(5) Quan Ke; Wang Jiaoli; Li Jing; Wang Kemin; Huang Jin*. An endogenous miRNA-initiated hybridization chain reaction and subsequent DNAzyme activation for cellular theranostics,CCS Chemistry, 2022, 4:3505-3515.
(6) Quan Ke; Yi Cuiping; Yang Xiaohai; He Xiaoxiao; Huang Jin*; Wang Kemin*. FRET- based nucleic acid probes: Basic designs and applications in bioimaging, TrAC Trends in Analytical Chemistry, 2020, 124: 115784.
(7) Quan Ke; Li Jing; Wang Jiaoli; Xie Nuli; Wei Qiaomei; Tang Jinlu; Yang Xiaohai; Wang Kemin; Huang Jin*; Dual-microRNA-controlled double-amplified cascaded logic DNA circuits for accurate discrimination of cell subtypes. Chemical Science, 2019, 10: 1442-1449.
(8) Quan Ke; Huang Jin*; Yang Xiaohai; Yang Yanjing; Ying Le; Wang He; Xie Nuli; Ou Min; Wang Kemin*; Powerful amplification cascades of FRET-based two-layer nonenzymatic nucleic acid circuits. Analytical Chemistry, 2016, 88: 5857-5864.
(9) Quan Ke; Huang Jin; Yang Xiaohai; Yang Yanjing; Ying Le; Wang He; He Yong; Wang Kemin*; An enzyme-free and amplified colorimetric detection strategy via target-aptamer binding triggered catalyzed hairpin assembly. Chemical Communications, 2015, 51: 937-940.